Chelsea romped to a 3-0 win over AC Milan at Stamford Bridge in the Champions League last Wednesday and the Serie A giants will be after revenge when the teams lock horns at the San Siro on Tuesday.
Goals from Wesley Fofana, Pierre-Emerick Aubameyang and Reece James earned Chelsea maximum points on Matchday 3 in the Champions League but Milan have since beaten Juventus in Serie A and an open contest looks on the cards in Italy.
Chelsea, meanwhile, followed up their win over Milan with a victory by the same scoreline against Wolves on Saturday.
Milan are still in the midst of an injury crisis and, although defender Theo Hernandez is back in action, forward Charles De Ketelaere has joined a lengthy list of absentees featuring Zlatan Ibrahimovic, Mike Maignan, Junior Messias, Alessandro Florenzi, Alexis Saelemaekers, Simon Kjaer and Davide Calabria.
As for Chelsea, they are set to be without Fofana, who came off injured against Milan last week, and industrious midfielder N’Golo Kante, who is still working his way back to full fitness.
Chelsea have made a strong start to life under Graham Potter, winning three and drawing one of the four matches they have played under his stewardship.
But, despite their loss to the Blues last week, Milan are also going well right now and have managed four wins in their last six games in all competitions.
Their expansive style of play has seen them involved in some high-scoring games this term and four of their last six matches have seen both teams score and over 2.5 goals.
Rafael Leao has been particularly dangerous on the flank for Milan, managing to score and assist 11 times in as many games this season.